All other active attack modifier work with instant attacks. Only these 3 don't.

Their interaction with instant attack got recently "fixed". The "fix" was, they simply got disabled for instant attacks. It's a bad fix.

Instead, they should work like Walrus Punch: Apply their effects on the first target they hit, and then go on cooldown and expend mana.

In the video, you can see how all of them work, except the named 3. If they have a mana cost, they drain mana for each hit enemy. If they have a cooldown, they hit the first enemy and go on cooldown without affecting further enemies. Burning Spears even drains hp for each hit enemy.